VThunter

a database for single-cell screening of virus target cells in animal kingdom

Mongolian horse

Scientific Name: Equus caballus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Perissodactyla-> Equidae-> Equus-> Equus

Human immunodeficiency virus 1

Family: Reoviridae

Receptor: CXCR4

Receptor CXCR4 information

Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_0066	2021.04	iDrop	PBMC	Normal	12794	Link

Featureplot of receptors

mRNA expression of CXCR4 in human tissues [NCBI]

Expression: Biased expression in bone marrow (RPKM 479.2), lymph node (RPKM 201.0) and 9 other tissues?

Protein expression of CXCR4 in human tissues [Proteinatlas]